How We Innovate
Supercharging Nature Through Intelligent Protein Design
It’s time to rethink how products are made.
Our Intelligent Protein Design Technology™ combines computational design and AI to create entirely new designer proteins and enzymes more efficiently and with less risk. It’s our way of supercharging what happens all the time in nature. Here’s a look at how we do it.
Intelligent Protein
Design
Technology™
Computational Protein Design & AI
We examine more combinations of amino-acids than there are drops of water in the Pacific Ocean to create in-silico proteins and enzymes with specific functional properties to address business and sustainability needs.
We examine countless combinations of amino acids to create in-silico proteins and enzymes with specific functional properties.
DNA Synthesis
Using our dedicated software and lab robotics, we build the synthetic DNA that encodes the exact protein sequences designed by our algorithms.
We build synthetic DNA that encodes the exact protein sequences designed by our algorithms.
Precision Lab Testing
By utilizing our precision design software, as opposed to serendipitous protein engineering, we test a targeted number of new proteins. This means we can test each design in application relevant conditions, as opposed to relying on a high-throughput reporter assay that doesn’t correlate with what matters to our customers.
Utilizing our precision design software, we test a targeted number of new proteins in application-relevant conditions.
Data Storage,
Analysis & Learning
We store all data generated, from expression to functional activity, in our proprietary databases. Using deep learning, we not only use the data to inform the next round of design, but also continuously improve our protein design algorithms to optimize functional properties and efficiencies at scale.
We store all data generated in our proprietary databases and use deep learning to continuously improve our protein design algorithms to optimize function and scale.
Steeped In Science
Our team of scientists and engineers are steeped in industry experience and scientific research with a mission to solve some of today’s hardest challenges through protein innovation.
From developing some of the most advanced deep learning and physics-based methods for protein design, to breakthrough synthetic biology and automation, to scalable, industrial-grade manufacturing process development, our team brings the experience to solve some of the hardest problems the industry – and humanity – is facing.
Our Heritage
And our heritage as a company co-founded by David Baker, PhD and associated with the Institute of Protein Design ensures we have direct access to the premier academic advances in protein design.
Our Passion
Published Research From Our Team
We’re pioneers in enzyme and protein design. Take a look at the peer-reviewed published research, handbooks and scientific papers from our founders, Scientific Advisory Board and team members which continue to inform and advance the scientific community:
An Enumerative Algorithm for de Novo Design of Proteins with Diverse Pocket Structures (2020)
PNAS
Efficient Minimization of Multipole Electrostatic Potentials in Torsion Space (2018)
PLOS
Epitope-Focused Immunogen Design Based on the Ebolavirus Glycoprotein HR2-MPER Region (2022)
PLOS
Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein (2017)
Structure
De Novo Computational Enzyme Design (2014)
ScienceDirect
Accurate Design Of Co-Assembling Multi-Component Protein Nanomaterials (2015)
Science
“Computational Protein Design” in Protein Engineering Handbook (2012)
Wiley-VCH
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Dills-Alder Reaction (2010)
Science
Kemp Elimination Catalysts By Computational Enzyme Design (2008)
Nature
De Novo Computational Design of Retro-Aldol Enzymes (2008)
Science
Contact Us
Our goal is to help you reach yours. Get in touch with our team today and reimagine what’s possible with Arzeda: